Description

Epigenetics of Stress and Stress Disorders, a new volume in the Translational Epigenetics series, examines the epigenetic
mechanisms involved in modifying DNA following prolonged stress or trauma. This is accomplished through the
evaluation of both the physiological and molecular effects of stress on the body that can eventually lead to stress
disorders. The book begins by providing a psychiatric, biological, and phenomenological foundation for understanding
stress disorders, before delving into the genomics of stress disorders. From here, chapter authors discuss a range of
recent epigenetic research in the area, highlighting epigenome-wide association studies (EWAS), exciting developments
in noncoding RNA studies, possible effects of prolonged stress on telomere shortening, and the long-term physical
effects of PTSD on the health of patients. The book also examines the effect of adversity during sensitive periods or
development and across the life span. The book concludes by looking at possible transgenerational stress-induced
epigenetic alterations on future offspring and important areas of research for public health, along with the potential for
epigenetic therapeutics or "epidrugs."