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  7. Preparation and Evaluation of Magnetic Microspheres of Mesalamine

Preparation and Evaluation of Magnetic Microspheres of Mesalamine

Remedy for Patients Stricted to Ulcerative Colitis

Satinder Kakar, Ramandeep Singh
Livre broché | Anglais
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Description

When a patient has no alternative towards treatment of disease then Magnetic microspheres come into view.Magnetic Microspheres have basically two advantages that is Reticuloendothelial clearance can be minimised and target site specificity can be increased.For Drug targeting, various carrier systems have been exploited like liposomes, nanospheres, microspheres, macromolecules etc. The difficulty of targeting drugs in vivo using these carrier systems is that the body contains 3 major tubes: the vascular, extracellular & intracellular compartments. Despite having several advantages, one most important problem to this field is that all the systems so far developed, give release rates that are either constant or decrease with time. Microspheres are successfully utilized for drug targeting but they show poor site specificity and are rapidly cleared off by RES (reticuloendothelial system) under normal circumstances.Improvement of patient compliance can be accomplished by this method. 1)Although magnetic nanoparticles, emulsions, liposomes can be made but they are less stable than magnetic microspheres. 2) Magnetic microspheres are easily recyclable and can be used in different fields.

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Contenu

Nombre de pages :
160
Langue:
Anglais

Caractéristiques

EAN:
9783848483525
Date de parution :
11-03-14
Format:
Livre broché
Dimensions :
150 mm x 220 mm
Poids :
245 g

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