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Formulating Poorly Water Soluble Drugs

Livre relié | Anglais | Aaps Advances in the Pharmaceutical Sciences | n° 50
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Description

The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist's approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound's physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facetsand detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.

Spécifications

Parties prenantes

Editeur:

Contenu

Nombre de pages :
693
Langue:
Anglais
Collection :
Tome:
n° 50

Caractéristiques

EAN:
9783030887186
Date de parution :
20-05-22
Format:
Livre relié
Format numérique:
Genaaid
Dimensions :
178 mm x 254 mm
Poids :
1433 g

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