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- 7.000.000 titres dans notre catalogue
- Payer en toute sécurité
- Toujours un magasin près de chez vous
The Base Excision Repair Pathway
Molecular Mechanisms and Role in Disease Development and Therapeutic Design
Livre relié | Anglais
459,45 €
+ 918 points
Description
This book will serve as the preeminent text book on the topic of "base excision repair", a key DNA repair pathway that protects cells from most spontaneous forms of DNA damage, including oxidative lesions that arise both in the nuclear and mitochondrial genomes. The book, which includes contributions from many of the world leaders in the field, provides a detailed description of the molecular mechanisms of base excision repair, as well as its emerging relationship to epigenetic regulation, the aging process and human disease, such as cancer susceptibility, immunological defects and neurological disorders. The book will also cover the state-of-the-art technologies being developed to assess base excision repair capacity among individuals in the population, in addition to the strategies being employed to target base excision repair as part of therapeutic paradigms to eradicate disease, namely cancer.
This book represents one of the most extensive efforts to date to cover the topic of "base excision repair". It includes chapters by many of the most established investigators in the field, from all over the world.
Spécifications
Parties prenantes
- Editeur:
Contenu
- Nombre de pages :
- 824
- Langue:
- Anglais
Caractéristiques
- EAN:
- 9789814719728
- Date de parution :
- 09-02-17
- Format:
- Livre relié
- Format numérique:
- Genaaid
- Dimensions :
- 160 mm x 231 mm
- Poids :
- 1451 g
